Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe

Clostridium difficile-associated diarrhea in a region of Quebec from 1991 to 2003: a changing pattern of disease severity

Jean‐Louis Pépin · Canadian Medical Association Journal · 2004 · 1.1K citations · Full text

Medicine, Infectious Diseases, Pathology +17

Emergence of Fluoroquinolones as the Predominant Risk Factor for Clostridium difficile-Associated Diarrhea: A Cohort Study during an Epidemic in Quebec

Jean‐Louis Pépin, Nabil Saheb, Marie‐Andrée Coulombe et al. · Clinical Infectious Diseases · 2005 · 997 citations

Medicine, Infectious Diseases, Pharmacotherapy +13

Increasing Risk of Relapse after Treatment of Clostridium difficile Colitis in Quebec, Canada

Jean‐Louis Pépin, M.-E. Alary, Louis Valiquette et al. · Clinical Infectious Diseases · 2005 · 573 citations · Full text

Medicine, Infectious Diseases, Pharmacotherapy +13

Production of actin-specific ADP-ribosyltransferase (binary toxin) by strains of Clostridium difficile

Simon Stubbs, Maja Rupnik, Maryse Gibert et al. · FEMS Microbiology Letters · 2000 · 436 citations · Full text

Life Sciences, Microbiology, Molecular Biology +16

Clostridium difficile toxin B is more potent than toxin A in damaging human colonic epithelium in vitro.

Martin Riegler, Roland Sedivy, Charalabos Pothoulakis et al. · Journal of Clinical Investigation · 1995 · 345 citations · Full text

Life Sciences, Pathobiology, Mechanisms Of Toxicity +13