Concepedia

The role of lipopolysaccharide in infectious bone resorption of periapical lesion

Chi‐Yuan Hong, Sze‐Kwan Lin, Sang‐Heng Kok, Shih‐Jung Cheng, Ming‐Shu Lee, Tong‐Mei Wang, C S Chen, Li‐Deh Lin, Juo‐Song Wang

Journal of Oral Pathology and Medicine · 2004 · 155 citations · 25 references

DOI

Abstract

It is suggested that LPS released from the infected root canal triggers the synthesis of IL-1 alpha and TNF-alpha from macrophages. These pro-inflammatory cytokines up-regulate the production of MMP-1 by macrophages to promote periapical bone resorption.

References

25

A New Method for the Extraction of R Lipopolysaccharides

Chris Galanos, O. Lüderitz, Otto Westphal · European Journal of Biochemistry · 1969 · 1.9K citations

, , +16

Rat macrophage lysosomal membrane antigen recognized by monoclonal antibody ED1.

Jan Damoiseaux, Ed A. Döpp, Wim Calame et al. · PubMed · 1994 · 521 citations · Full text

, , +19

Associations between microbial species in dental root canal infections

G. Sundqvist · Oral Microbiology and Immunology · 1992 · 426 citations

, , +13

Influence of combinations of oral bacteria on periapical tissues of monkeys

Lars Fabricius, Gunnar Dahlén, Stig E. Holm et al. · European Journal Of Oral Sciences · 1982 · 311 citations

Initiation of Osteoclast Bone Resorption by Interstitial Collagenase

L. Shannon Holliday, Howard G. Welgus, Catherine J. Fliszar et al. · Journal of Biological Chemistry · 1997 · 245 citations · Full text

, , +14