Platelet-platelet and platelet-leukocyte interactions induced by outer membrane vesicles from N. meningitidis

Abstract

Meningococcal-derived OMVs as well as purified meningococcal LPS, contribute to increased platelet-platelet and platelet-leukocyte aggregation and may thus be of great importance in the development of microthrombosis and organ dysfunction related to fulminant meningococcal septicemia.