Aldose Reductase Inhibitor Fidarestat Attenuates Leukocyte-Endothelial Interactions in Experimental Diabetic Rat Retina<i>In Vivo</i>

Abstract

Oral administration of fidarestat attenuated leukocyte accumulation in the retina of STZ induced-diabetic rats, suggesting that fidarestat may have a therapeutic role in preventing the progression of diabetic retinopathy.