Concepedia

Metabolism of Intravenous Methylnaltrexone in Mice, Rats, Dogs, and Humans

Appavu Chandrasekaran, Zeen Tong, Hongshan Li, John C. L. Erve, William DeMaio, Igor Goljer, Oliver J. McConnell, Yakov Rotshteyn, T A Hultin, Rasmy Talaat,

Drug Metabolism and Disposition · 2010 · 28 citations · 22 references

DOI

Concepts

References

22

The double-blind, randomized, placebo-controlled trial

Ted J. Kaptchuk · Journal of Clinical Epidemiology · 2001 · 601 citations

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Methylnaltrexone for Reversal of Constipation Due to Chronic Methadone Use

Chun‐Su Yuan, Joseph Foss, Michael O’Connor et al. · JAMA · 2000 · 298 citations

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Methylnaltrexone prevents morphine-induced delay in oral-cecal transit time without affecting analgesia: A double-blind randomized placebo-controlled trial*

Chun‐Su Yuan, Joseph Foss, Michael O’Connor et al. · Clinical Pharmacology & Therapeutics · 1996 · 215 citations

, , +17

Effects of Subcutaneous Methylnaltrexone on Morphine-Induced Peripherally Mediated Side Effects: A Double-Blind Randomized Placebo-Controlled Trial

Chun‐Su Yuan, Gang Wei, Joseph Foss et al. · Journal of Pharmacology and Experimental Therapeutics · 2002 · 116 citations

, , +17

Metabolism and disposition of naltrexone in man after oral and intravenous administration.

Monroe E. Wall, Dolores R. Brine, Mario Perez‐Reyes · Drug Metabolism and Disposition · 1981 · 111 citations

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