Regio and stereoselective synthesis of β-keto functionalized C-glycosides via iron catalyzed Ferrier rearrangement reactions

Abstract

An efficient iron-catalyzed <italic>C</italic>-glycosylation method has been established. Starting from glycals and β-keto acids, a wide range of β-keto-functionalized 2,3-unsaturated <italic>C</italic>-glycosides have been synthesized in moderate to good yields with reasonable selectivities <italic>via</italic> decarboxylative Ferrier rearrangement reaction.