Up-regulation of Tiam1 and Rac1 Correlates with Poor Prognosis in Hepatocellular Carcinoma

Abstract

The current study demonstrated for the first time that the Tiam1-Rac1 pathway may play a critical role in tumor progression of hepatocellular carcinoma. The expression of Tiam1 and Rac1 can be considered as the two useful indicators for predicting the prognosis of hepatocellular carcinoma.