Myocardial Fibrosis in Transforming Growth Factor β1Heterozygous Mice

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

Anita B. Roberts, Michael B. Sporn, Richard K. Assoian et al. · Proceedings of the National Academy of Sciences · 1986 · 2.9K citations · Full text

Tissue Engineering, Engineering, Rapid Induction +18

Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.

Ronald A. Ignotz, Joan Massagué · Journal of Biological Chemistry · 1986 · 2.5K citations · Full text

Fibrosis, Developmental Biology, Systems Biology +12

Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor.

Dylan R. Edwards, Gillian Murphy, John J. Reynolds et al. · The EMBO Journal · 1987 · 1.2K citations · Full text

Developmental Biology, Connective Tissue Disease, Human Growth +8

Natural inhibitor of transforming growth factor-β protects against scarring in experimental kidney disease

Wayne A. Border, Nancy A. Noble, Tatsuo Yamamoto et al. · Nature · 1992 · 972 citations

Urology, Medicine, Renal Pathology +13

A nuclear factor 1 binding site mediates the transcriptional activation of a type I collagen promoter by transforming growth factor-β

Pellegrino Rossi, Gérard Karsenty, Anita B. Roberts et al. · Cell · 1988 · 621 citations

Growth Factor-β, Transcriptional Regulation, Developmental Biology +11