Concepedia

Expeditious synthesis of saponin P57, an appetite suppressant from Hoodia plants

Jian Zhang, Hefang Shi, Yuyong Ma, Biao Yu

Chemical Communications · 2012 · 37 citations · 31 references

DOI

Concepts

Abstract

Pregnane glycoside P57, the appetite suppressant component from Hoodia, was synthesized expeditiously, featuring preparation of the aglycone Hoodigogenin A from digoxin and assembly of the deoxytrisaccharide with glycosyl o-alkynylbenzoates as donors.

References

31

Readily accessible 12-I-5 oxidant for the conversion of primary and secondary alcohols to aldehydes and ketones

D. B. DESS, J. C. Martin · The Journal of Organic Chemistry · 1983 · 3.1K citations

, , +15

A Rapid Esterification by Means of Mixed Anhydride and Its Application to Large-ring Lactonization

Junji Inanaga, Kuniko Hirata, Hiroko SAEKI et al. · Bulletin of the Chemical Society of Japan · 1979 · 2.2K citations

, , +16

Synthesis of .alpha.,.beta.-unsaturated carbonyl compounds by palladium(II)-catalyzed dehydrosilylation of silyl enol ethers

Yoshihiko Ito, Toshikazu Hirao, Takeo Saegusa · The Journal of Organic Chemistry · 1978 · 849 citations

, , +12

The Preparation and Synthetic Utility of <i>tert</i>-Butyldiphenylsilyl Ethers

Stephen Hanessian, Pierre Lavallée · Canadian Journal of Chemistry · 1975 · 434 citations

, , +10

Iodine(V) Reagents in Organic Synthesis. Part 4. <i>o</i>-Iodoxybenzoic Acid as a Chemospecific Tool for Single Electron Transfer-Based Oxidation Processes

K. C. Nicolaou, Tamsyn Montagnon, Phil S. Baran et al. · Journal of the American Chemical Society · 2002 · 420 citations

, , +13