A small-sized graphene oxide supramolecular assembly for targeted delivery of camptothecin

Abstract

A small-sized graphene oxide supramolecular assembly was obtained by the inclusion complexation of hyaluronated adamantane with β-cyclodextrin and the π-stacking of graphene oxide with camptothecin, exhibiting an excellent stability in the serum environment and a higher inhibition effect toward malignant cells than a free drug.