Pharmacologically Increasing Mdm2 Inhibits DNA Repair and Cooperates with Genotoxic Agents to Kill p53-Inactivated Ovarian Cancer Cells - Concepedia

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Pharmacologically Increasing Mdm2 Inhibits DNA Repair and Cooperates with Genotoxic Agents to Kill p53-Inactivated Ovarian Cancer Cells

29

Citations

25

References

2015

Year

Alexia M. Carrillo, Mellissa Hicks, Dineo Khabele, Christine M. Eischen

Molecular Cancer Research

Abstract

Data reveal a therapeutically beneficial effect of pharmacologically increasing Mdm2 levels combined with chemotherapeutic agents for malignancies that have lost functional p53.

References

	Year	Citations

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