Characterization of Wound Reepithelialization Using a New Human Tissue-Engineered Corneal Wound Healing Model

Abstract

The similarity observed with the in vivo wound healing process supports the use of this tissue-engineered model for investigating the basic mechanisms involved in corneal reepithelialization. Moreover, this model may also be used as a tool to screen agents that affect reepithelialization or to evaluate the effect of growth factors before animal testing.