Neolignan, Flavonoid, Phenylethanoid and Iridoid Glycosides from Phlomis integrifolia

Abstract

From the aerial parts of Phlomis integrifolia Hub.-Mor. (Lamiaceae) were isolated a neolignan glucoside, dehyrodiconiferyl alcohol-4-O-b -D-glucopyranoside (1), an ester flavone glycoside, chrysoeriol 7-O-(3''-O-trans-p-coumaroyl)-b -D-glucopyranoside (2), four phenylethanoid glycosides, forsythoside B (3), verbascoside (=acteoside) (4), leucosceptoside A (5) and martynoside (6) along with an iridoid glucoside, lamiide (7). The structure elucidation of the isolated compounds was carried out by spectroscopic (UV, IR, 1D- and 2D-NMR) methods. The isolation of neolignan glucoside dehyrodiconiferyl alcohol-4-O-b -D-glucopyranoside (1) is reported for the first time from a Phlomis species as well as for the family Lamiaceae.