Reverse Transcriptase Inhibitors Down-Regulate Cell Proliferation<i>in Vitro</i>and<i>in Vivo</i>and Restore Thyrotropin Signaling and Iodine Uptake in Human Thyroid Anaplastic Carcinoma

Abstract

These findings support the need for clinical trials to clarify whether RT inhibitors may restore the sensitivity to radiometabolic therapy in anaplastic thyroid tumors.