Reviewing old concepts at the start of a new millenium: Growth restriction, adrenal hypoplasia, and thymomegaly in human anencephaly

Abstract

Our results suggest that adrenal hypoplasia is invariably present in anencephaly, and depending on an underdeveloped pituitary gland, seems to be independent of its etiology. On the contrary, IUGR mainly exists in associated cases and thymus enlargement mainly exists in isolated cases, suggesting a relationship with the underlying cause.