Infection and Immunity · 2004 · 109 citations · 40 references
Life SciencesGeneticsMicrobiologyMicrobial GeneticsMicrobial PathogenesisMycologyFungal Cell BiologyFungal GeneticsFungal PathogenesisFungal PhysiologyYeast BiologyYeast GeneticsAgarCandida Albicans InfectionCandida-host InteractionsFungal Gene ExpressionFungal Gene RegulationFungal Transcriptional RegulationMutant IdentificationYeast Gene Regulation
The SKN7 two-component response regulator gene of Candida albicans was deleted, and the phenotype of the mutant was established. This mutant exhibited impaired growth on Spider agar and 10% serum agar compared to wild-type and gene-reconstituted strains. The skn7 mutant was sensitive to H(2)O(2) in vitro, but its virulence was only mildly attenuated. A comparison of the Skn7p and Ssk1p response regulators of C. albicans is discussed.
40
Colorimetric Method for Determination of Sugars and Related Substances
Michel Dubois, K. A. Gilles, J. K. Hamilton et al. · Analytical Chemistry · 1956 · 51.8K citations
Agriculture, Chemistry, Food Science +13
Isogenic strain construction and gene mapping in Candida albicans.
William A. Fonzi, M Y Irwin · Genetics · 1993 · 1.7K citations · Full text