Autosomal recessive lissencephaly with cerebellar hypoplasia is associated with a loss-of-function mutation in CDK5

Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds

Dominik Mumberg, Rolf Müller, Martin Funk · Gene · 1995 · 2K citations

Protein Expression, Yeast Vectors, Genetics +10

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death.

Toshio Ohshima, Jerrold M. Ward, C G Huh et al. · Proceedings of the National Academy of Sciences · 1996 · 893 citations · Full text

Developmental Biology, Signal Transduction, Apoptosis +15

Autosomal recessive lissencephaly with cerebellar hypoplasia is associated with human RELN mutations

Susan E. Hong, Yin Yao Shugart, David T. Huang et al. · Nature Genetics · 2000 · 875 citations

Developmental Anomaly, Developmental Biology, Mendelian Disorder +8

A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size

Jacquelyn Bond, Emma Roberts, Kelly Springell et al. · Nature Genetics · 2005 · 562 citations

Molecular Neuroscience, Neurophysiology, Neuroanatomy +11

NUDEL Is a Novel Cdk5 Substrate that Associates with LIS1 and Cytoplasmic Dynein

Martin Niethammer, Deanna S. Smith, Ramsés Ayala et al. · Neuron · 2000 · 480 citations · Full text

Protein Function, Signal Transduction, Natural Sciences +9