Loss of Function in Heparan Sulfate Elongation Genes <i>EXT1</i> and <i>EXT 2</i> Results in Improved Nitric Oxide Bioavailability and Endothelial Function - Concepedia

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Publication | Open Access

Loss of Function in Heparan Sulfate Elongation Genes <i>EXT1</i> and <i>EXT 2</i> Results in Improved Nitric Oxide Bioavailability and Endothelial Function

DOI Full Paper Access

26

Citations

32

References

2014

Year

Hans L. Mooij, Pedro Cabrales, Sophie J. Bernelot Moens, Ding Xu, S D Udayappan, Amy G. Tsai, Michiel A. J. van de Sande, E. de Groot, Marcos Intaglietta, John J.P. Kastelein,

Journal of the American Heart Association

Abstract

Our data implicate that heparan sulfate elongation genes EXT1 and EXT2 are involved in maintaining endothelial homeostasis, presumably via increased nitric oxide bioavailability.

References

	Year	Citations

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