The Journal of Organic Chemistry · 1998 · 186 citations · 15 references
PharmacyMedicinal ChemistryPharmacologyDrug DiscoveryStructure-activity RelationshipsSynthetic Medicinal ChemistryMarine Bioactive CompoundsMarine Drug DiscoveryMarine Natural Product BiosynthesisMarine Natural ProductsMarine PharmacologyStructure-activity Relationship AnalysisBioactive Compounds From Marine CoralsBioactive Compounds From Marine SpongesMarine PharmacognosyMarine Sponge MetabolitesMarine Sponge Natural Product BiosynthesisSponges As Drug SourcesSponges-derived MetabolitesSynthetic Analogs Of Marine Natural Products
The strongly cytotoxic, antibiotic, and immunosuppressive palau'amine was isolated from the Belau sponge Stylotella aurantium, along with less active 4-bromo and 4,5-dibromo derivatives. Three corresponding isomeric compounds, all less active, were also isolated, and full details of the isolation and all structure proofs are provided.
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Alkaloids from the antarctic sponge Kirkpatrickia varialosa.
Nigel B. Perry, Laurent Ettouati, Marc Litaudon et al. · Tetrahedron · 1994 · 177 citations
New tetrodotoxin analogs from the newt Cynops ensicauda
Takeshi Yasumoto, Mari Yotsu, Michio Murata et al. · Journal of the American Chemical Society · 1988 · 157 citations