A highly diastereoselective, catalytic three-component assembly reaction for the synthesis of spiropyrrolidinyloxindoles

Chris V. Galliford, James S. Martenson, Charlotte Stern, Karl A. Scheidt

Chemical Communications · 2006 · 49 citations · 49 references

Concepts

Abstract

Spiropyrrolidinyloxindole compounds are synthesized in moderate to excellent yield via a highly diastereoselective Cu(I)-catalysed three-component assembly reaction of an imine, diazo-compound and substituted olefin dipolarophile.

References

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