Pathologic changes of glial cells in murine model of Niemann–Pick disease type C: Immunohistochemical, lectin‐histochemical and ultrastructural observations

Abstract

In the murine model of NPC, astrocytes and oligodendrocytes are also involved in the morbid processes. Thus, it might be relevant to investigate the glial dysfunction to understand the pathological processes of the disease and to prepare an adjunct therapeutic strategy to manage the patients with NPC.