Size Effect on Cell Uptake in Well‐Suspended, Uniform Mesoporous Silica Nanoparticles

Abstract

The size of it: Mesoporous silica nanoparticles (MSNs) of controlled size in the range 30 to 280 nm are obtained by adjusting the pH of the reaction solution. The uptake of fluorescein-labeled MSNs (green, see image) by HeLa cells is size-dependent, with maximum uptake at a nanoparticle size of 50 nm.