Bone loss in premenopausal, perimenopausal and postmenopausal women: results of a prospective observational study over 9 years

Abstract

Women in the menopausal transition lose trabecular bone at a rapid rate despite intermittently high and usually normal estrogen levels. This is the only prospective study to date that documents trabecular bone changes in women through the entire perimenopause, which may last up to 10 years.