Statins Enhance Rotator Cuff Healing by Stimulating the COX2/PGE2/EP4 Pathway

Abstract

Although chronic inflammation contributes to the development of tendinopathy, study results advocate for a positive role of PGE2 in tendon healing during the acute inflammatory phase that follows tendon surgical repair. It is therefore suggested that ATV should be further investigated as a possible modality to improve tendon healing.