5‐(Ethoxymethylene)thiazolidine‐2,4‐dione Derivatives: Reactions and Biological Activities

Abstract

Abstract The 5‐(ethoxymethylene)‐4‐thioxothiazolidin‐2‐ones 2a‐c were synthesized and reacted with acrylonitrile, ethyl acrylate. β‐nitrostyrene, N ‐phenylmaleimide and malononitrile under different conditions, to yield the cycloaddition products 3–14. The antibacterial and antifungal activities of the new products were tested.