Plasma perfusion by apheresis through a Gal immunoaffinity column successfully depletes anti‐Gal antibody: experience with 320 aphereses in baboons

Abstract

(1) With appropriate monitoring, EIA is an acceptably safe procedure, even in small (<10 kg) baboons. (2) Three consecutive EIAs are effective in removing >97% of Gal Ab. (3) In the majority of cases, return of Gal Ab begins within 24 h, irrespective of the immunomodulatory protocol.