Beneficial effect of the 5‐HT_1A receptor agonist buspirone on esophageal dysfunction associated with systemic sclerosis: A pilot study

Abstract

The beneficial acute effect of buspirone on impaired LES function associated with SSc suggests a role of 5-HT1A receptor-mediated interactions in these patients. Prospective studies to examine whether buspirone is of long-term therapeutic value for SSc-associated esophageal disease are warranted.