Concepedia

β(1-3)Glucanosyltransferase Gel4p Is Essential for Aspergillus fumigatus

Amandine Gastebois, Thierry Fontaine, Jean‐Paul Latgé, Isabelle Mouyna

Eukaryotic Cell · 2010 · 97 citations · 15 references

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Abstract

The beta(1-3)glucanosyltransferase GEL family of Aspergillus fumigatus contains 7 genes, among which only 3 are expressed during mycelial growth. The role of the GEL4 gene was investigated in this study. Like the other Gelps, it encodes a glycosylphosphatidylinositol (GPI)-anchored protein. In contrast to the other beta(1-3)glucanosyltransferases analyzed to date, it is essential for this fungal species.

References

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Glycosylphosphatidylinositol-anchored Glucanosyltransferases Play an Active Role in the Biosynthesis of the Fungal Cell Wall

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