Assessment of Circulating Sex Steroid Levels in Prepubertal and Pubertal Boys and Girls by a Novel Ultrasensitive Gas Chromatography-Tandem Mass Spectrometry Method

Frédérique Courant, Jean‐Philippe Antignac, Fabrice Monteau, Kaspar Sørensen, Anna‐Maria Andersson, Niels E. Skakkebæk, Anders Juul, Bruno Le Bizec

The Journal of Clinical Endocrinology & Metabolism · 2009 · 170 citations · 37 references

Abstract

Using an accurate and sensitive method, we found significantly higher levels of estrogens as well as androgen metabolites in prepubertal girls compared with age-matched boys. The higher prepubertal sex steroid levels in girls may contribute to their earlier onset of puberty including pubic hair development.

References

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