Concepedia

Publication | Open Access

Therapeutic Efficacy of AAV1.SERCA2a in Monocrotaline-Induced Pulmonary Arterial Hypertension

DOIFull Paper Access

116

Citations

31

References

2013

Year

Lahouaria Hadri, Razmig Garo Kratlian, Ludovic Bénard, Bradley A. Maron, Peter Dorfmüller, Dennis Ladage, Christophe Guignabert, Kiyotake Ishikawa, Jaume Agüero, Borja Ibáñez,
Circulation

Abstract

Downregulation of SERCA2a plays a critical role in modulating the vascular and right ventricular pathophenotype associated with PAH. Selective pulmonary SERCA2a gene transfer may offer benefit as a therapeutic intervention in PAH.

References

YearCitations

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