Intrarectal Treatment of 100 Cases of Ulcerative Colitis with Prednisolone-21-phosphate Enemata

Abstract

MEDICAL JOURNALshowed active inflammation, as indicated by the presence of polymorphs in the mucosa.In patients who had been without symptoms for six or less months, the great majority, 14 out of 17, had an abnormal mucosa.histologically, and in 13 of these it also appeared abnormal on sigmoidoscopy.However, the patients without symptoms for more than six months were different.About one-half showed a normal appear- ance by sigmoidoscopy and the other half abnormal, but of the 15 cases whose appearances were normal eight had an abnormal mucosa microscopically.This