Inhibitory Effect of Oral Doxycycline on Neovascularization in a Rat Corneal Alkali Burn Model of Angiogenesis

Abstract

Oral doxycycline inhibits CNV without the harmful side effects associated with dexamethasone use. Further investigation is warranted to assess the mechanisms through which doxycycline acts to cause CNV inhibition, and the applicability of doxycycline use for treating CNV in the clinical setting.