Journal of Zoo and Wildlife Medicine · 2014 · 13 citations · 12 references
MedicineAnimal SciencesContraceptionReproductive EndocrinologyReproductive PhysiologyEstrous CycleReproductive ManagementReproductive Pathology In WildlifeEstrous Cycle MonitoringEstrous Cycle PhasesHigh-resolution UltrasonographyOvarian HormonesReproductive Health In WildlifeZoo Animal ManagementZoo Animal Welfare
Contraception is necessary to manage zoo animal populations and to be able to house animals in groups without producing additional unwanted offspring. In felids and canids, an association between exposure to progestins and the occurrence of endometrial and mammary gland pathology has been documented. Therefore, the Association of Zoos and Aquariums (AZA) Wildlife Contraceptive Center recommends the use of deslorelin acetate for long-term contraception in carnivores. Return to cyclicity after deslorelin treatment has been variable; some individuals show ovarian suppression for long periods after the expected end of the deslorelin efficacy. In an attempt to reduce the time to reversal, techniques to locate and remove previous implants are being developed. This report documents the successful implementation of high-frequency ultrasonography in lions (Panthera leo) to locate and direct surgical removal of multiple deslorelin implants placed at least 2 yr previously as well as the return of follicular activity in both females at 7 months post-removal of implants.
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Efficacy of the GnRH analogue deslorelin for suppression of oestrous cycles in cats.
L. Munson, Joan E. Bauman, C S et al. · PubMed · 2001 · 112 citations
Ernest Loumaye, Kevin Catt · Journal of Biological Chemistry · 1983 · 101 citations · Full text
Ulysses S. Seal, E. D. Plotka, James D. Smith et al. · Biology of Reproduction · 1985 · 69 citations