Impairment of Growth of<i>Listeria monocytogenes</i>in THP‐1 Macrophages by Granulocyte Macrophage Colony‐Stimulating Factor: Release of Tumor Necrosis Factor–α and Nitric Oxide

Abstract

GM-CSF impairs the intracellular growth of L. monocytogenes by a synergistic action of the GM-CSF-triggered release of autocrine TNF-alpha and hydrogen peroxide and the production of NO (associated with the stimulation of the expression of iNOS).