Clinical Infectious Diseases · 2009 · 36 citations · 7 references
MedicineNeurologyOphthalmologyNeuro-ophthalmologyOcular DiseaseOcular PharmacologyEye DiseaseMedication Effects On VisionNeuro-ophthalmic DisordersOptic NeuritisOptic NeuropathiesAcute Bilateral Vision LossDrug-induced Ocular ToxicityInfectious Optic NeuropathyLinezolid TherapyMedication-induced NeuropathyOptic Nerve Injury
A patient undergoing chemotherapy for treatment of acute lymphocytic leukemia developed septicemia that was treated with linezolid for 16 days. The patient subsequently reported reduced vision in both eyes and was found to have bilateral optic neuropathy. After the discontinuation of linezolid treatment, both the optic neuropathy and visual impairment resolved without sequelae.
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Linezolid-Induced Inhibition of Mitochondrial Protein Synthesis
An S. De Vriese, Rudy Van Coster, Joél Smet et al. · Clinical Infectious Diseases · 2006 · 318 citations
Linezolid-induced Optic Neuropathy
Tomohiro Saijo, Keiko Hayashi, Hideyuki Yamada et al. · American Journal of Ophthalmology · 2005 · 53 citations
Gary C. Brown, Jerry A. Shields, James J. Augsburger et al. · International Ophthalmology · 1981 · 48 citations
Medicine, Oncology, Ophthalmology +16