Chromogenic <i>in situ</i> hybridization for Her‐2/neu‐oncogene in breast cancer: comparison of a new dual‐colour chromogenic <i>in situ</i> hybridization with immunohistochemistry and fluorescence <i>in situ</i> hybridization

Abstract

CISH, using dual-colour probes (ZytoVision) is as good as FISH for Her-2/neu analysis. The few discrepant results are likely to be caused by polysomy or tumour heterogeneity.