Concepedia

Reductions in muscle sympathetic nerve activity after long-term metoprolol for dilated cardiomyopathy: preliminary observations.

Md Ashiqur Rahman, Kazuhiro Hara, Paul Daly, E.Douglas Wigle, John S. Floras

Heart · 1995 · 30 citations · 24 references

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Abstract

Muscle sympathetic nerve activity and calf vascular resistance decrease in patients with dilated cardiomyopathy who improve after long term treatment with metoprolol. Inhibition of central sympathetic outflow may be one mechanism by which metoprolol benefits such subjects.

References

24

Echocardiographic determination of left ventricular mass in man. Anatomic validation of the method.

R DEVEREUX, Nathaniel Reichek · Circulation · 1977 · 4.5K citations · Full text

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Plasma Norepinephrine as a Guide to Prognosis in Patients with Chronic Congestive Heart Failure

Jay N. Cohn, T. Barry Levine, Maria Teresa Olivari et al. · New England Journal of Medicine · 1984 · 3.1K citations

Beta 1- and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure.

Michael R. Bristow, Robert Ginsburg, Victor A. Umans et al. · Circulation Research · 1986 · 1.3K citations · Full text

, , +13

Beneficial effects of metoprolol in idiopathic dilated cardiomyopathy

Finn Waagstein, Åke Hjalmarson, Karl Swedberg et al. · The Lancet · 1993 · 1.2K citations

, , +6

Norepinephrine spillover to plasma in patients with congestive heart failure: evidence of increased overall and cardiorenal sympathetic nervous activity.

Gregory J. Hasking, Murray Esler, Garry Jennings et al. · Circulation · 1986 · 1K citations · Full text

, , +14