Gut · 1999 · 220 citations · 32 references
MedicinePathologyRadiologyDiagnostic RadiologyGastroenterologyUltrasonographyAbdominal ImagingAbdominal UltrasonographyAbdominal UltrasoundColonic DiseasesGastrointestinal ImagingInflammatory Bowel DiseaseAbscess Detection ImagingComplications Of Intestinal ObstructionCrohn Disease PathologyDiagnostic Test ProceduresImaging Of AbscessesInflammatory Bowel Disease PathologyIntra-abdominal Abscess
BACKGROUND: The course of Crohn's disease is characterised by the occurrence of intestinal complications such as strictures, intra-abdominal fistulas, or abscesses. Standard diagnostic procedures may fail to show these complications, in particular fistulas. AIMS: To test the value of transabdominal bowel sonography (T) for the detection of intestinal complications in Crohn's disease. METHODS: T was prospectively performed in 213 patients with Crohn's disease in a university based inflammatory bowel disease referral centre. Thirty three underwent resective bowel surgery and were included in this study. The accuracy of T to detect strictures, intra-abdominal fistulas, or abscesses was compared with surgical and pathological findings. RESULTS: T was able to identify strictures in 22/22 patients and to exclude it in 10/11 patients (100% sensitivity, 91% specificity). Fistulas were correctly identified in 20/23 patients and excluded in 9/10 patients (87% sensitivity, 90% specificity). Intra-abdominal abscesses were correctly detected in 9/9 patients and excluded in 22/24 patients (100% sensitivity, 92% specificity). CONCLUSIONS: In experienced hands T is an accurate method for the detection of intestinal complications in Crohn's disease. T is thus recommended as a primary investigative method for evaluation of severe Crohn's disease.
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A SIMPLE INDEX OF CROHN'S-DISEASE ACTIVITY
Richard F. Harvey, J.M. Bradshaw · The Lancet · 1980 · 3K citations
Long-term follow-up of patients with Crohn's disease
Richard G. Farmer, Gregory Whelan · Gastroenterology · 1985 · 446 citations
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P J Haggett, N.R. Moore, John Shearman et al. · Gut · 1995 · 191 citations · Full text