Publication | Open Access
Ionic liquid catalyzed convenient synthesis of imidazo[1,2-a]quinoline under sonic condition
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2012
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Asymmetric CatalysisIonic LiquidChemical EngineeringEasier Work-upEngineeringHeterocyclicBenign ProcedureIonic ConductorOrganic ChemistryCatalysisChemistryHeterocycle ChemistryUltrasound IrradiationDeep Eutectic SolventSynthetic ChemistryEnantioselective Synthesis
An efficient protocol for the synthesis of imidazo[1,2-a]quinoline from aldehydes, enaminones, and malononitrile using 1,8-diazabicyclo[5.4.0]-undec-7-en-8-ium acetate ([DBU][Ac]) as a catalyst under ultrasound irradiation is described. Compared with other methods, this new method has the advantages of easier work-up, milder reaction conditions, high yields and environmentally benign procedure.