Intermolecular [2+2] Reaction of <i>N</i>‐Allenylsulfonamides with Vinylarenes: Enantioselective Gold(I)‐Catalyzed Synthesis of Cyclobutane Derivatives

Abstract

Golden touch: N-allenylsulfonamides react with styrene derivatives to furnish chiral cyclobutanes in both high yield and enantioselectivity at −70 °C. Phosphoramidite ligands such as 1, facilitate this asymmetric gold(I)-catalyzed [2+2] cycloaddition. Tf=trifluoromethanesulfonyl.