The earlier, the smaller, the better for natalizumab-associated PML: In MRI vigilance veritas?

Abstract

Natalizumab-associated progressive multifocal leukoencephalopathy (N-PML) in multiple sclerosis (MS) is due to CNS infection by the opportunistic JC virus (JCV). As of December 2011, 193 confirmed cases of N-PML have been observed, giving rise to an overall risk of approximately 0.202%.[1][1] N-PML