The Effect of Chemical Modification and Nanoparticle Formulation on Stability and Biodistribution of siRNA in Mice

Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency

Hai‐Quan Mao, Krishnendu Roy, Vu L. Troung-Le et al. · Journal of Controlled Release · 2001 · 1.2K citations

Pharmacy, Biotechnology, Molecular Pharmaceutics +16

Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors

Erwei Song, Pengcheng Zhu, Sang‐Kyung Lee et al. · Nature Biotechnology · 2005 · 1K citations

Pharmacy, Molecular Biology, Pharmaceutics +14

Impact of tumor-specific targeting on the biodistribution and efficacy of siRNA nanoparticles measured by multimodality <i>in vivo</i> imaging

Derek W. Bartlett, Helen C. Su, Isabel J. Hildebrandt et al. · Proceedings of the National Academy of Sciences · 2007 · 797 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +17

RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo

Beata Urban-Klein, Stephanie Werth, Shaker Abuharbeid et al. · Gene Therapy · 2004 · 707 citations

Pharmacy, Biotechnology, Molecular Biology +14

Therapeutic <i>EphA2</i> Gene Targeting <i>In vivo</i> Using Neutral Liposomal Small Interfering RNA Delivery

Charles N. Landen, Arturo Chávez‐Reyes, Corazon D. Bucana et al. · Cancer Research · 2005 · 672 citations

Pharmacy, Oncology, Pharmacology +17