NDRG1 promotes the multidrug resistance of neuroblastoma cells with upregulated expression of drug resistant proteins

Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.

Thomas G. Graeber, Jeff Peterson, Mitchell H. Tsai et al. · Molecular and Cellular Biology · 1994 · 614 citations · Full text

P53 Status, Cell Death, P53 Protein +18

Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants

Michael T. Hemann, Anka Bric, Julie Teruya‐Feldstein et al. · Nature · 2005 · 449 citations

Tumor Heterogeneity, Medicine, Tumour-derived Myc Mutants +6

The Drg-1 gene suppresses tumor metastasis in prostate cancer.

Sucharita Bandyopadhyay, Sudha K. Pai, Steven Gross et al. · PubMed · 2003 · 313 citations

Oncology, Malignant Disease, Medicine +11

Drg-1 as a differentiation-related, putative metastatic suppressor gene in human colon cancer.

Rong Guan, Heide L. Ford, Yineng Fu et al. · PubMed · 2000 · 312 citations

Drg-1 Cdna, Tumor Biology, Human Colon Cancer +13

NDRG1 Is Necessary for p53-dependent Apoptosis

Susanne Stein, Emily K. Thomas, Birger Herzog et al. · Journal of Biological Chemistry · 2004 · 215 citations · Full text

P53-dependent Apoptosis, Ndrg1 Gene, Apoptosis +9