Comparison of modes of ascertainment for mosaic vs complete trisomy 21

First-Trimester or Second-Trimester Screening, or Both, for Down's Syndrome

Fergal D. Malone, Jacob A. Canick, Robert H. Ball et al. · New England Journal of Medicine · 2005 · 1.1K citations · Full text

Medicine, Gynecology, Obstetrics +17

A screening program for trisomy 21 at 10–14 weeks using fetal nuchal translucency, maternal serum free β‐human chorionic gonadotropin and pregnancy‐associated plasma protein‐A

Kevin Spencer, Vivienne Souter, Natasha Tul et al. · Ultrasound in Obstetrics and Gynecology · 1999 · 571 citations

Medicine, Maternal Health, Obstetrics +17

First-Trimester Screening for Trisomies 21 and 18

Ronald J. Wapner, Elizabeth Thom, Joe Leigh Simpson et al. · New England Journal of Medicine · 2003 · 567 citations · Full text

Medicine, Genetics, Obstetrics +17

Integrated Screening for Down's Syndrome Based on Tests Performed during the First and Second Trimesters

Nicholas Wald, Hilary Watt, Allan Hackshaw · New England Journal of Medicine · 1999 · 537 citations · Full text

Medicine, Maternal Health, Obstetrics +17

Improved National Prevalence Estimates for 18 Selected Major Birth Defects--United States, 1999-2001

JAMA · 2006 · 298 citations · Full text

Public Health, Obstetrics, Pediatrics +16