THE EFFECT OF BILATERAL STELLECTOMY UPON THE CEREBRAL CIRCULATION OF MAN 1

Abstract

The role of the sympathetic nervous system in the intrinsic control of the cerebral circulation has always been controversial. Experiments heretofore have centered on the effects of stimulation of the cervical sympathetic nerves on changes in cerebral blood flow detected by instruments applied directly to the brain of animals. The results have generally agreed that cervical sympathetic stimulation causes only mild cerebral vasoconstriction. The marked effects of chemical agents (CO2 in particular) in affecting the cerebral circulation have led to the probably correct conclusion that the intrinsic control of the cerebral circulation in health is predominantly mediated via chemical agents in the blood and that neurogenic vasomotor control is at best only