Nevirapine or efavirenz for tuberculosis and HIV coinfected patients: exposure and virological failure relationship*

Abstract

The omission of the 2 week lead-in dose of nevirapine prevented low concentrations at treatment initiation but did not prevent the risk of virological failure. Results support the WHO recommendation to use efavirenz at 600 mg daily in patients on rifampicin-based antituberculosis therapy.