Involvement of nitrergic system in the anticonvulsant effect of the cannabinoid CB1 agonist ACEA in the pentylenetetrazole-induced seizure in mice

Unresponsiveness to Cannabinoids and Reduced Addictive Effects of Opiates in CB ₁ Receptor Knockout Mice

Catherine Ledent, Olga Valverde, G Cossu et al. · Science · 1999 · 3.6K citations

Medicine, Neuroscience, Pharmacology +15

Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses

Rachel I. Wilson, Roger A. Nicoll · Nature · 2001 · 1.6K citations

Life Sciences, Neurobiology, Neuroscience +14

CB1 Cannabinoid Receptors and On-Demand Defense Against Excitotoxicity

Giovanni Marsicano, Sharon Goodenough, Krisztina Monory et al. · Science · 2003 · 1.2K citations

Medicine, Neuroscience, Pharmacology +17

Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice

Andreas Zimmer, Anne Zimmer, Andrea G. Hohmann et al. · Proceedings of the National Academy of Sciences · 1999 · 1.1K citations

Medicine, Neuroscience, Pharmacology +9

Tests of the roles of two diffusible substances in long-term potentiation: evidence for nitric oxide as a possible early retrograde messenger.

Thomas J. O’Dell, Robert D. Hawkins, Eric R. Kandel et al. · Proceedings of the National Academy of Sciences · 1991 · 1K citations

Life Sciences, Neurobiology, Neuroscience +17