Does titration of mitomycin C as an adjunct to trabeculectomy significantly influence the intraocular pressure outcome?

Abstract

The outcome of trabeculectomy with adjunctive MMC appears to represent a complex interaction of patient and surgical variables. While there is some support for a benefit of titrating MMC according to individual patient variables, there is inadequate evidence at the present time to claim superiority for any MMC protocol, with or without titration.