Concepedia

Publication | Open Access

Defective Regulation of Interdomain Interactions Within the Ryanodine Receptor Plays a Key Role in the Pathogenesis of Heart Failure

DOIFull Paper Access

148

Citations

23

References

2005

Year

Tetsuro Oda, Masafumi Yano, Takeshi Yamamoto, T Tokuhisa, Shinichi Okuda, Masahiro Doi, Tomoko Ohkusa, Yasuhiro Ikeda, Shigeki Kobayashi, Noriaki Ikemoto,
Circulation

Abstract

The specific domain interaction within the RyR regulates the channel gating property, and the defectiveness in the mode of the interdomain interaction seems to be the initial critical step of the pathogenesis of heart failure.

References

YearCitations

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