Antimicrobial Agents and Chemotherapy · 2008 · 62 citations · 22 references
Life SciencesInfectious DiseasesMicrobiologyAntimicrobial ResistanceBacteriologyMedical MicrobiologyAntibiotic ResistanceAntibiotic Resistance GeneticsBacterial EpidemiologyPlasmid BiologyPlasmid GeneticsPlasmid GenomicsAntibiotic Resistance PlasmidsBroad-host-range PlasmidsMacrolide Resistance GenesMacrolide Resistance PlasmidsPlasmid - Host InteractionsPlasmid Host RangePlasmid-borne Antibiotic ResistancePlasmid-borne Resistance
Twenty-three isolates of group A streptococci (GAS) recovered from population-based invasive GAS surveillance in the United States were erythromycin resistant, inducibly clindamycin resistant, and lacked known macrolide resistance determinants. These 23 isolates, representing four different clones, contained a broad-host-range plasmid carrying the erm(T) methylase gene, which has not been detected in GAS previously.
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